n their review published in BioEssays, Mahesh Sangrithi and James Turner discuss mammalian X chromosome dosage compensation with a particular focus on the germ line.
Life Science
Raman Spectroscopy as a Diagnostic Tool for Skin Cancer
A team of German researchers created a new multimodal system for rapid, noninvasive in vivo skin cancer screening is presented, combining optical coherence tomography (OCT) and optoacoustic (OA) modalities to provide precise tumor depth determination with a Raman spectroscopic modality capable of detecting the lesion type and, thus, providing diagnostic capability.
Evolution of Post-Transcriptional Gene Regulation
“DNA makes RNA makes protein”? After transcription, mRNAs undergo a series of ‘post‐transcriptional’ regulatory processes to be finally translated into functional proteins. Changes in these regulatory processes are important driving forces underlying the evolution of phenotypic differences across different species.
Disassembly at the Micro-Scale: Classification of Three Distinct Types of Microautophagy
In their article published in BioEssays, Masahide Oku and Yasuyoshi Sakai present three distinct types of microautophagy.
New Simple Biomarker Imaging Technique for Critical Diseases
A simple optical imaging technique for biomarker analysis for critical diseases.
A Light Touch: Reversible Control over Enzyme Activity
A new inhibitor of glutamate transporter enzymes can be turned ‘on’ and ‘off’ using different wavelengths of light.
CRISPR-based Genome Editing via Non-Viral Delivery
This non-viral CRISPR-Cas9 delivery vector is ten times as effective at genome modification as the standard plasmid transfection techniques, down-regulating Plk1 expression over 70% to inhibit tumor growth.
Invader Cells as Delivery Vesicles for Various Cargo Molecules
A smart cell-targeting approach for potential use in specific cell ablation.
New 3D In Vivo Imaging Approach for Functional Assessment of Oviduct
A 3D imaging approach that enables prolonged functional assessment of the mouse oviduct (or fallopian tube) in vivo.
What is a Stem Cell?
Discussing the historical roots of the stem cell concept and the definition generally adopted today.
Popular
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Micron-sized hidden dimensions could solve two of physics’ deepest puzzles
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Turning Periods into Power: Menstrual Blood a Valuable Resource for Medical Diagnostics
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Surfactants Steer Supraparticle Structure
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Bone loss in obesity traced to gut microbiota
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Edible electronics realize safe, complex monitoring devices
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Fermilab Confirms Muon g-2 Measurements