A DNA carrier with RNA incorporated into its vertices overcomes the problem of delivering treatments into joints for osteoarthritis patients.
Therapeutics
Laser-guided nanoparticles could improve drug delivery to the back of the eye
Smarter delivery systems for retinal disease treatments could reduce how often patients need injections.
Wearable headband combines AI and mindfulness to alleviate car sickness
A novel brain–computer interface shifts the attention of passengers to relieve even severe car sickness.
Controversial Gene Therapy for Alzheimer’s Disease
Glial-to-neuron conversion therapy decreases inflammation and restores the brain-blood barrier in Alzheimer’s disease model macaques.
AI pipelines correctly identify genetic basis for disease even without medical training
Large language models use reasoning capabilities to identify new genetic factors causing disease.
Regenerative Gel Treats Female Infertility Caused by Intrauterine Adhesions
Extracellular vesicles in hydrogels allow cell-free therapy for intrauterine adhesions, including recovery of reproductive functions.
Lipid nanoparticles: from trial-and-error to mechanism-based design
Individual components of lipid nanoparticles are examined to understand how they interact with cells.
Drug-free hair regrowth via cold plasma treatments
Using cold plasma, researchers are targeting the hair follicle microenvironment to encourage hair regrowth.
Honeysuckle’s therapeutic potential for Inflammatory Bowel Disease
Traditional Chinese medicine inspires research into the benefits of honeysuckle for reducing inflammation and correcting gut bacteria imbalance in inflammatory bowel disease.
Tiny vesicles could help prevent amputations in diabetic patients
This safer, non-surgical treatment for diabetic limb ischemia could help patients with severe blood flow complications.
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Metabolic–Epigenetic Link Between Sleep Deprivation and Immune Dysregulation