A protocol for a unique high-throughput assay to identify novel small-molecule inhibitors of cell migration.
Therapeutics
Prickly Nanoparticles against Cancer
The fabrication of a specific nanomedicine, prickly shaped nanoparticles, enables a novel cancer treatment methodology.
Two-in-One: A Copolypeptide Provides Antimicrobial Activity and Barrier Properties
A new approach to prevent wound infections: Antimicrobial activities and microbial barrier properties can be designed in a single biopolymer.
Breaching the Tumor Barrier – A Novel pH-sensitive Drug Delivery System
A novel pH-sensitive anticancer drug delivery system with improved therapeutic effect.
The Great Hope: Biomaterial Methods for Spinal Cord Injury Treatment
Combinatorial strategies that use biomaterials for regeneration of the injured central nervous system.
High Throughput and High Content Imaging: The Special Issue Returns
The recently published Part II Special Issue on High Throughput and High Content Imaging and Cellular Informatics.
Advanced Goes Bio: Welcome to Advanced Biosystems
The first issue of Advanced Biosystems highlights retinal implants, DNA nanotweezers, and living diodes.
Preparing Brain Tumors for Therapy
Matrix-metalloprotease (MMP)-sensitive hydrogel particles intend to utilize the unique properties of tumor cells, such as high concentration of MMP enzymes, along with the synergistic activities of an apoptosis-inducing protein (TRAIL) and the TRAIL sensitizer drug Quinacrine.
Magnetic Healing of Brain Injury
Advanced natural multi-functional biomaterials may one day help heal brain injury.
Making Insulin Producing Beta Cells by Cell Reprogramming
A robust and reproducible method for “direct programming” of acinar cells into functional beta cells with a polycistronic viral construct and viral transduction of pancreatic tissue in vivo in mice is described.
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