Self-propelling microparticles enhance the dissolution of drugs in the stomach, achieving better bioavailability without the side effects of high dosing.
Therapeutics
Step-closer to nasal spray drug delivery for Parkinson’s disease
A new drug-laden gel allows for better levels of uptake in both the blood and the brain.
Breaching the wall: How malaria parasites enter the human brain
Researchers uncover how malaria infiltrates the blood–brain barrier and contributes to disease severity.
Keeping immune cells in check to ward off diabetes
Bioengineered pancreatic beta cells adorned with immune checkpoint proteins prevent the progression of type 1 diabetes.
Microneedle patch delivers antibiotics locally in the skin
A microneedle patch that delivers antibiotics directly into the affected skin area could help treat deadly bacterial infections.
3D-bioprinted breast cancer to understand tumor growth and spread
A prototype platform allows researchers to culture and study tumor growth in new detail.
Brain implants with a short and sweet solution
Pudding-like implants with a sugar-based delivery system show promise in reducing the foreign body response against brain implants.
Accurate diagnosis and treatment of early-stage lung cancer
Polypeptides that selectively induce calcification of cancer cells could improve early detection and limit the progression of lung cancer.
Trojan horse inspires novel treatment for Parkinson’s disease
In this study, a drug to treat Parkinson’s disease is linked to a molecule that enables it to better penetrate the brain.
Multicellular liver-on-a-chip for modeling fatty liver disease
A structurally representative liver-on-a-chip models the full progression of non-alcoholic fatty liver disease, which researchers hope will lead to better treatments.
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