The first issue of Advanced Biosystems highlights retinal implants, DNA nanotweezers, and living diodes.
Biotechnology
Engineering the Biomolecular Machinery for Synthetic Biological Circuits
The control of gene expression is an important tool for metabolic engineering, the design of synthetic gene networks, gene-function analysis, and protein manufacturing. This review article discusses the potential of the modular design of novel regulatory proteins fashioned after the topology and mechanochemical properties of the lactose repressor.
Nanoescapology: Progress toward Understanding the Endosomal Escape of Polymeric Nanoparticles
An introduction to the mechanisms governing internalization and trafficking in cells; and a discussion of methods to detect endosomal escape and recent advances in controlling endosomal escape from polymer- and lipid-based nanoparticles are presented in this recent Review.
Heart Stem Cell Therapy in Patches
Vascularized cardiac patch provides a cell home for a patient’s own stem cells for drug screening and a personalized tissue graft.
Rapid, Low Cost Detection of E.coli and Shigella
A 16S rRNA targeting oligonucleotide probe to improve target organism specificity and lowers costs for detection of low-level E. coli/Shigella contamination.
Bioactive Shape Memory Mats
Temperature responsive fibers from shape memory polymers are assembled into bioactive mats or scaffolds.
Biofibers Made from Green Lacewing Silk
Innovative biofibers made from a silk protein of the green lacewing are being developed at the Fraunhofer IAP in conjunction with AMSilk.
Gold Nanoparticle-Mediated Photothermal Therapy: Applications and Opportunities for Multimodal Cancer Treatment
Photothermal therapy that uses gold nanoparticles to convert light to heat is effective against cancer both alone and combined with other therapeutic strategies is reviewed.
Ocular Drug Delivery Powered by Your Body
Researchers from Singapore, China and USA have recently reported in Advanced Materials the first example of a TENG-based self-powered iDDS, and demonstrate its functionality in ocular drug delivery.
Magnetic Nanoparticle-Mediated Gene Delivery to Neural Stem Cells
The first description on the use of oscillating magnetic fields for magnetic nanoparticle-mediated (MNP) gene transfer to neural stem cells NSCs.
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