Bioinspired, biohybrid device design and fabrication strategy for investigating the ability of therapeutics to cross the blood brain barrier.
Therapeutics
Targeted, ROS-Promoted Nanomedicine for Cancer Treatment
A novel reactive oxygen species (ROS)-promoted nanomedicine platform can effectively inhibit tumor growth, reduce side effects experienced in common anticancer drugs, while promote on-target uptake.
![Tumor-Targeting “Polywraplex” for siRNA Delivery [Video]](https://www.advancedsciencenews.com/wp-content/uploads/2018/02/ASN_feature_adfm201703207.jpg)
Tumor-Targeting “Polywraplex” for siRNA Delivery [Video]
Tuo Jin and colleagues from Shanghai Jiao Tong University synthesize a synthetic carrier system for small interfering RNA (siRNA) with customizable size, pH-responsive degradability, and optimized surface population of cell-targeting agent.
Immunoengineering with Biomaterials for Enhanced Cancer Immunotherapy
Biomaterials are engineered to improve the safety and efficacy of current cancer immunotherapies.
Noncoding RNAs in Alzheimer’s Disease
New directions in which ncRNAs can be exploited in Alzheimer’s disease prevention, diagnosis, prognosis, and therapy are discussed.
Multifunctional Titania Now Ready for Medical Imaging and Photodynamic Therapy?
Multifunctional gadolinium-doped titania nanoparticles perform combined diagnostics and treament without compromising the advantages of their components.
Cover Art – Biomaterials, Cancer Nanomedicine and Macroporous Hydrogels
Latest Advanced Healthcare Materials covers.
Emerging Roles of RNA Binding Proteins in Diabetes
RNA binding proteins are implicated in diabetes-associated pathogenic events as they initiate pathogenic signals that can cause mitochondrial dysfunction, fibrosis, inflammation and epithelial mesenchymal transition (EMT).
Electrically Driven Bio-Inspired Soft Robots
Researchers design a bio-inspired batoid robot from non-toxic hydrogels operated with Au microelectrodes.
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