To fight antibiotic-resistant pathogens, and to ensure wide-spread application and high compliance, oral vaccinations are desirable, but pose drug delivery complications. An efficient nanoparticle system for vaccination against stomach ulcer causing Helicobacter pylori was recently reported.
Envisioning the Future of Polymer Therapeutics for Brain Disorders
Polymer therapeutics represent promising novel chemical entities under development for addressing CNS disorders, in which intravenous and intranasal administration are the most appealing strategies to achieve this paramount goal.
Advanced Protocol for Modeling Retinal Pigment Epithelium-related Diseases
Advanced protocol for high quality primary human retinal pigment epithelium stem cell-derived cultures
Chemically Engineered Fusion Proteins beyond Nature’s Machinery
Bioactive entities are combined into structurally ordered multidomain protein complexes to mitigate selective targeting of a hallmark protein molecule in cancer diseases.
Cover Art: Patient-Specific Bioinks & Wound Healing
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Biopolymers Murray Goodman Memorial Prize Symposium
William F. DeGrado receives the Murray Goodman Memorial Prize at the ACS Spring National meeting 2018.
A Rapid In Situ Disinfection Method for Surgical Implants [Video]
A disinfection method for titanium implant surfaces using a hybrid coating of chitosan on molybdenum disulfide.
TB Off: Fighting Tuberculosis with Magnetic Triggers
New magnetically-activated drug delivery systems offer a potentially more effective tool to fight tuberculosis
Cover Art – Theranostics, Pre-Metastatic Niche and Bone Regeneration
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CRISPR-based Genome Editing via Non-Viral Delivery
This non-viral CRISPR-Cas9 delivery vector is ten times as effective at genome modification as the standard plasmid transfection techniques, down-regulating Plk1 expression over 70% to inhibit tumor growth.