A team of researchers from the University of North Carolina and the University of Washington introduce therapeutic nanoparticles that enhance the delivery of brain-derived neurotrophic factor (BDNF) to the brain for therapy of neurological diseases.
A team of researchers from the University of North Carolina and the University of Washington introduce therapeutic nanoparticles that enhance the delivery of brain-derived neurotrophic factor (BDNF) to the brain for therapy of neurological diseases.
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Group I intron-based trans-splicing ribozyme specifically recognizes disease-specific RNA, removes the sequence downstream of the target site, and replaces it with a 3’-exon encoding a therapeutic/reporter RNA sequence, inducing therapeutic/reporter activity selectively in the target RNA-expressing cells.
A biosensor based on SERS to detect lung cancer volatile organic compound (VOC) from exhaled breath.
Cecilia Leal from the University of Illinois and co-workers summarize the current research on lipid-based films for biomedical applications and provide new insight into multilayered hybrid lipid–polymer films for substrate-mediated drug delivery.
Nanocarriers can be precision-engineered to capitalize on what is known about receptor expression patterns, receptor clustering, and ultimately how interactions between a nanocarrier and target can be manipulated to achieve the most effective downstream signaling events.
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Clinical translation of stem cell therapies requires clear definition and characterization of the cell populations, especially in a biologically diverse group of non-human mammalian species.
Synthetic cells that function as autonomous systems for producing an anti-cancer protein inside the body are developed.