While it might not feel like it, the cells in our body are under constant stress. Cellular exposure to stress such as UV radiation contributes to DNA lesions that the cell responds to by initiating DNA repair pathways. If these lesions are not dealt with, mutations...
Understanding the nature and origin of the non-coding genome.
A caterpillar prepares for its legendary transformation from a pupa into a colorful butterfly. Through this metamorphosis, a bag of developmental genetic tricks lays down bright color patterns that help the butterfly attract its mates and warn or fool its predators.
This week’s Advanced Healthcare Materials cover manuscripts.
Parameters that affect the biological performance of particles and highlight strategies for improved targeting ability of particles.
Applications of Subset Selection Procedures and Bayesian Ranking Methods in Analysis of Traffic Fatality Data
In this article, a new Bayesian model is developed and applied to the traffic fatality data and the results contrasted to those obtained with the subset selection procedures.
Charting the Genotype-Phenotype Map: Lessons From the Drosophila melanogaster Genetic Reference Panel
An advanced review recently published in WIREs Developmental Biology summarizes insights about the genetic basis of variation of quantitative traits from the many GWA analyses of morphological, behavioral, life history and other traits that have been published to date using the DGRP and populations derived from it.
Methods to capture protein-RNA interactions. Different techniques are required to capture single-stranded (green), double-stranded (blue), and indirect (yellow) RNA interactions. Crosses (X) in red mark RNA sites that are crosslinked to the RNA binding protein.
A new review by Lennox et al discuss recent advances in our understanding of post-transcriptional regulation during embryonic cerebral cortex development.
This month’s top Advanced Healthcare Materials papers.
Segmental Arithmetic: Summing Up the Hox Gene Regulatory Network for Hindbrain Development in Chordates
It is important to understand when and how the hindbrain segmentation program evolved. Recent studies have shed some light.
A new journal from the Advanced Materials family covering all aspects of theory and simulation in natural sciences is launching in early 2018.