Annals of the New York Academy of Sciences has published this year’s installment of the annual reviews series The Year in Diabetes and Obesity, edited by Rexford Ahima (The Johns Hopkins University School of Medicine). Founded in 2010, the series—one of eight published in Ann NY Acad Sci—has a dedicated Editorial Advisory Board of distinguished researchers.
Type 2 Diabetes (T2D) is a prevalent form of diabetes, a metabolic disease that results in high blood sugar levels. Over 420 million adults worldwide suffer from diabetes and ~1.5 million of them die from it each year (WHO). The most common types of diabetes are chronic insulin-deficient Type 1 Diabetes (T1D), chronic insulin-resistant T2D, prediabetes, and temporary gestational diabetes. Roughly 90% of all diabetes cases is attributed to T2D, and 90% of those suffering from T2D are overweight or obese (with a body mass index (BMI) of 30 and greater).
Although the exact mechanisms of how T2D develops in overweight and obese patients are still not fully understood, there is a direct and obvious correlation between T2D and excess body fat. The Year in Diabetes and Obesity presents 12 review articles summarizing the latest developments in basic, translational, and clinical research concerning this important topic.
The following three review articles are highlighted on the cover:
Deciphering adipose tissue heterogeneity
Matthew D. Lynes, Yu‐Hua Tseng
Insulin regulation of gluconeogenesis
Maximilian Hatting, Clint D.J. Tavares, Kfir Sharabi, Amy K. Rines, Pere Puigserver
Precision medicine in diabetes: an opportunity for clinical translation
Jordi Merino, Jose C. Florez
