April’s top Advanced Healthcare Materials papers.
Therapeutics
Using “DNA Flowers” as Carriers for Protein Delivery
In-situ assembled flower-shaped DNA constructs can be used for an efficient intracellular protein delivery.
Bioinspired Extracellular Vesicles for Personalized Drug Delivery
Investigating EV production and purification methods by mimicking the natural release process of EVs in blood capillaries with a bioinspired mechanical microfluidic method.
Combating KRAS Mutant Metastatic Colorectal Cancer
A new targeted chemotherapeutic nano-medicine NANOPt-pan, composed of Panitumumab and DACHPt (the active form of Oxaliplatin), could passively and actively target EGFR over-expressing tumors and effectively target both KRAS wild type- and mutant-tumors.
Improving Cancer Photothermal Therapy: A How-To
Cancer is a disease that is responsible for an overwhelming number of deaths worldwide. The conventional therapeutic approaches used for treatment can be ineffective. inducing prominent side effects.
Using PyMOL as a Platform for Computational Drug Design
A recent review discusses various molecular modeling modules in PyMOL, covering those for visualization and analysis enhancement, protein-ligand modeling, molecular simulations and drug screening.
Nanotechnology Enhances Drug Delivery to the Back of the Eye
Nanotechnology possesses great potential to overcome shortcomings of existing strategies for safe and effective retinal drug delivery.
Ketosis Mimics the Life Span Expanding Powers of Caloric Restriction
Mechanisms of the action for ketosis in aging and extending life span are proposed in a recent review.
Nanotherapy Treatments Aim to Change Duchenne Muscular Dystrophy’s Outcome
A recent review discusses the emerging nanomedications and therapies with potential to alter Duchenne’s fatal outcome.
Targeted Nanoparticles for Head and Neck Cancer
Nanoparticles can assist in treatment of Head and Neck Cancer patients by optimizing distribution of chemotherapy drugs for better outcomes and less side effects.
Popular
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Micron-sized hidden dimensions could solve two of physics’ deepest puzzles
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Turning Periods into Power: Menstrual Blood a Valuable Resource for Medical Diagnostics
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Surfactants Steer Supraparticle Structure
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Bone loss in obesity traced to gut microbiota
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Edible electronics realize safe, complex monitoring devices
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Fermilab Confirms Muon g-2 Measurements