Katy Miller
Using Genome-Scale Metabolic Models for Human Diseases

Using Genome-Scale Metabolic Models for Human Diseases

Genome-scale metabolic models (GEMs) are relatively new tools for studying the metabolic changes associated with many diseases. GEMs are reconstructions of the metabolic networks of cells, sometimes able to represent an organism’s whole body.

How Can Protein Coronas Impact the Future of Nanomedicine?

How Can Protein Coronas Impact the Future of Nanomedicine?

The application and the clinical development of nanomedicines strongly requires a deep study on the complex dynamics that happen after in vivo administration. Particularly, plasma proteins tend to associate to nanoparticles, forming a new surface named the “protein corona” that can have a strong impact on biodistribution, targeting efficacy, and toxicity.