Nobel Prize for Medicine winners William Kaelin, Peter Ratcliffe, and Gregg Semenza “uncover a fundamental mechanism of life”.
Professor Masaki Inagaki talks to Advanced Science News as part of the 5th anniversary of Advanced Science.
Organelle-localized RNA recognition motif-containing proteins participate in a variety of RNA-related processes, including RNA editing, RNA processing, and RNA stability.
Interestingly, C. elegans is capable of a remarkable case of phenotypic plasticity, called the dauer stage, where it is capable of surviving without food for three months. (Image credit: D. Kucharski K. Kucharska/Shutterstock)
In live cells, many enhancer-binding transcription factors exchange rapidly with their binding sites and leave no footprints in chromatin. Available data suggests a highly dynamic mechanism for enhancer activation, involving numerous stochastic binding events at a target enhancer.
This week’s Advanced Healthcare Materials covers.
Various views on the same cell are discussed in a recent Special Issue on Monocytes and Marcophages.
This Review outlines the metabolic model design process and discusses the numerous choices for modeling frameworks and mathematical representations.
A review of methods that can be applied to study the control of proliferation (and the proliferative hierarchy, especially the role of the elusive stem cells) in a wide variety of animal models.
Researchers report a study on the proteins of the natural mummy of Cangrande della Scala (Prince of Verona, Northern Italy).
In their review in BioEssays, Ido Livneh et al. discuss recent findings that establish monoubiquitination as a proteasomal targeting signal.
The unmineralized teeth of the giant keyhole limpet are shown to have mechanical properties similar to those of mineralized mammalian bones.