Life Science
Serotonin Neuron Development: Shaping Molecular and Structural Identities

Serotonin Neuron Development: Shaping Molecular and Structural Identities

Serotonin neurons are highly plastic; their development, maturation and regeneration is controlled by a complex gene regulatory network in constant interaction with the environment. An overview article recently published in WIREs Developmental Biology offers an updated view of these fundamental developmental mechanisms, pointing to the many ways by which developmental dysfunction of serotonin systems might occur at different periods in life. This opens new possibilities for therapeutic intervention, which can range from prevention of risk to stem cell therapies.

Limbal Stem Cells for Treatment of Corneal Blindness

Limbal Stem Cells for Treatment of Corneal Blindness

Limbal stem cells have attracted a lot of interest in the field of regenerative medicine because of their unique ability to fully restore the whole cornea upon transplantation. Several important aspects of limbal stem cell biology are reviewed such as limbal stem cell identification, developmental origin and therapeutic potential.

mRNA Transport in Fungal Top Models

mRNA Transport in Fungal Top Models

The study of simple fungal model organisms provides valuable insights into fundamental mechanisms of mRNA transport boosting the understanding of similar events in higher eukaryotes.