Bacterial plasmids constitute a wealth of shared DNA amounting to about 20% of the total prokaryotic pangenome. Plasmids replicate autonomously and control their replication by maintaining a fairly constant number of copies within a given host. Plasmids should acquire a good fitness to their hosts so that they do not constitute a genetic load.
In their review published in BioEssays, Russell Fletcher, Diya Das and John Ngai discuss how the integration of lineage tracing with data obtained from single-cell RNA-sequencing can provide insights into how stem cells differentiate.
Using nano-pillars to change the way that neurons grow.
Recent advances in chromosome conformation capture technologies have led to the discovery of previously unappreciated structural features of chromatin.
In their ‘Think again’ article published in BioEssays, Megan Barnet and colleagues discuss how insights from fetal allografts and microbes can lead to a better understanding of immune tolerance in cancer.
The integrated stress response (ISR) is a highly-conserved pathway used by cells to respond to diverse cellular stresses.
Targeted viral-based gene therapies come with their own risks. A new gene delivery system mimics viral therapies to infect cancer cells with vesicular stomatitis virus matrix protein, with a similar transfection efficiency as the virus itself.
Thomas Larrieu and Carmen Sandi discuss whether social rank is a predictive risk factor for stress-induced depression.
Mohammad Soheilypour and Mohammad Mofrad discuss a technique termed ‘agent-based modeling’ that is used in systems biology.
An automated system to assemble macrotissues from prefabricated living microtissues with a cell density similar to organs is reported.
New theory suggests gravity is not a fundamental force
French WEST reactor breaks record in nuclear fusion
Quantum entanglement visualized for the first time ever
Higgs boson may be driving the Universe’s expansion
An anti-inflammatory peptide may hold the key to low-back pain relief
Could a nuclear explosion set Earth’s atmosphere on fire?
Black hole images deliver a deathblow to alternative theory of gravity
The Road to Better Presentation of Data: The Do’s and Don’ts
The dramatic story behind general relativity’s Nobel Prize snub
Researchers take a glimpse at the structure of rare tetraquarks