The potential of rapid diagnostics and screening has led to burgeoning interest in droplets, as it is increasingly used to detect novel disease biomarker targets.
The potential of rapid diagnostics and screening has led to burgeoning interest in droplets, as it is increasingly used to detect novel disease biomarker targets.
A simple optical imaging technique for biomarker analysis for critical diseases.
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This non-viral CRISPR-Cas9 delivery vector is ten times as effective at genome modification as the standard plasmid transfection techniques, down-regulating Plk1 expression over 70% to inhibit tumor growth.
A technique using gold nanoparticles and laser pulses can successfully destroy retinoblastoma cells.
Small molecules have been used to study several mammalian RNA elements in disease. These advances encourage exploration of newly discovered RNA interactions with therapeutic potential.
Ribosome production is a considerable energy investment for the cell—rRNAs and ribosomal proteins (RPs) are among the most abundant classes of RNAs and proteins—and their production must, therefore, be synchronized temporally and stoichiometrically to ensure efficient ribosome assembly.
A strategy to transform various photosensitizers into activatable ones for photodynamic therapy is reported.
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In their “Hypothesis” article published in BioEssays, Nirmalya Chatterjee and Dirk Bohmann discuss the interplay between Nrf2 and BET proteins and the resultant implications for therapies targeting these proteins.