In live cells, many enhancer-binding transcription factors exchange rapidly with their binding sites and leave no footprints in chromatin. Available data suggests a highly dynamic mechanism for enhancer activation, involving numerous stochastic binding events at a target enhancer.
Ingestion of engineered nanomaterials is inevitable due to their addition to food and prevalence in food packaging and domestic products such as toothpaste and sunscreen.
This week’s Advanced Healthcare Materials covers.
DNA and RNA (nucleic acids) interference therapies have the potential to treat many human diseases.
A DNA molecular machine powered by double-stranded fuel strands enables visualization of microRNAs in tumor bearing mice.
A Special Issue that reports on the latest technical developments in QPI used to study the mechanisms of cancer and neurodegenerative disorders, to develop multispecific pharmaceutical formulations, and as a robust segmentation technology for microbial cells.
In their review in BioEssays, Ido Livneh et al. discuss recent findings that establish monoubiquitination as a proteasomal targeting signal.
New protocols for the isolation of UC-MSCs are explored, including several helpful, individual protocols to aid quality control and ensure that the UC-MSCs are characterized thoroughly while improving yield.
An overview of the viability of different molecular simulation methods and interface force fields, the recent advances in the simulation of protein-surface interactions, and the challenges posed by the current simulation methods to reproduce the exact phenomenon.
New research has revealed that a pair of catalytic enzymes, called extracellular signal-regulated kinases 1 and 2 (ERK1/2), may play an essential role in the development of corneal blindness. (Image credit: MJTH/Shutterstock).
New theory suggests gravity is not a fundamental force
French WEST reactor breaks record in nuclear fusion
Quantum entanglement visualized for the first time ever
Higgs boson may be driving the Universe’s expansion
An anti-inflammatory peptide may hold the key to low-back pain relief
“Cosmic vine” discovered by the James Webb Space Telescope
Could a nuclear explosion set Earth’s atmosphere on fire?
Black hole images deliver a deathblow to alternative theory of gravity
The Road to Better Presentation of Data: The Do’s and Don’ts
The dramatic story behind general relativity’s Nobel Prize snub