DNA and RNA (nucleic acids) interference therapies have the potential to treat many human diseases.
Results for "DNA"
Glowing miRNA in vivo
A DNA molecular machine powered by double-stranded fuel strands enables visualization of microRNAs in tumor bearing mice.
Multiplex FRET Biosensor Simplifies Nucleic Acid Detection
Time-gated FRET-based biosensors allow the quantification of multiple nucleic acids at low nanomolar concentrations using just a single donor–acceptor pair.
Shiny New Scissors in the CRISPR/Cas9 Toolbox for Advanced Genome Editing
The CRISPR/Cas9 toolbox has been expanded with fluorescent Cas9 and a dCas9 functionalized with a tag able to activate gene expression that can be transfected to cells directly as ribonucleoprotein complexes (RNP).
Using PyMOL as a Platform for Computational Drug Design
A recent review discusses various molecular modeling modules in PyMOL, covering those for visualization and analysis enhancement, protein-ligand modeling, molecular simulations and drug screening.
Catching Antibodies with Protein Nanofibrils
Engineerined protein nanofibrils show a much higher binding capacity for antibody purification compared to current gold standard.
How Referencing Can Impact Reproducibility
Did you know that your citing habits can influence the reproducibility of your work?
Self-Gating Drug Delivery
Antitumour platform comes of age: this system gets the responsible drug to keep itself in check for transport and delivery.
Advanced Goes Bio: Welcome to Advanced Biosystems
The first issue of Advanced Biosystems highlights retinal implants, DNA nanotweezers, and living diodes.
Microexons: Discovery, Regulation, and Function
Microexon regulation has the ability to modulate protein properties, including mechanistic links to diseases like autism.
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