The active structure of an oral macrocyclic drug has eluded scientists for years despite its widespread clinical use—that is, until now.
Health
New local anesthetic delivery system offers longer lasting pain relief, fewer side effects
Hydrogel-based microspheres better control the release of drugs, providing better post-op pain relief and fewer side effects.
Tiny, self-propelled machines might be key to fighting antimicrobial resistance
Microscopic machines powered by light are a “double threat” to bacteria and could help combat the growing problem of drug resistance.
Gut-on-a-chip helps get to the bottom of inflammatory bowel disease
A microfluidic chip could help researchers uncover the unknown underlying mechanisms that cause inflammatory bowel disease.
A lung-mimicking sealant helps repair surgical leaks
A superior surgical sealant mimics the structural and mechanical properties of lung tissue to repair air leaks after surgery.
Wearable patch monitors blood sugar via sweat
An energy-harvesting wearable patch continuously monitors blood sugar levels via sweat to prevent hypoglycemic events in diabetic patients.
Nanovehicles take aim at tumor cells for better chemotherapy
Nanoparticles with innovative coatings target tumor cells, enhancing chemotherapy effectiveness while minimizing side effects.
Are dietary supplement labels accurate?
A new study finds that prescription generic galantamine and the over-the-counter supplement are not created equal, despite label claims.
Plant-based sunscreen ingredient gets a much-needed boost
Scientists have stabilized the natural product sanshool, a promising active ingredient for sunscreen and skincare products.
Researchers uncover a fundamental driver behind osteoarthritis
The first link between biomolecule concentration in our cartilage and the progression of osteoarthritis opens new routes for treatment.
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