Similar to eukaryotes, prokaryotic cells can spatiotemporally regulate localization of RNAs, which is crucial for the survival and proper function of these tiny organisms.
Researchers explore the different mechanisms viruses have evolved to effectively seize host cell ribosomes, and the role they play in the virus’ life cycle.
RNA-related processes that are key to the biology of the cell are at risk during coronavirus infections.
RNA plays a fundamental role in our health and biology, and advancements in imaging techniques are expanding our understanding of its life cycle.
RNA elements that are found in the genomes of numerous representatives within the same virus family provide new opportunities to expand the repertoire of targets for the development of antiviral therapy.
A blackboard of therapeutic innovation: Researchers seek to understand how antisense oligonucleotides can “erase” disorders.
Understanding how mRNA localization changes during healthy brain functions and pathological conditions.
Every gene found in our DNA exerts its action via the activity of its encoded protein product. However, the synthesis of the protein cannot take place directly from the gene. An intermediate messenger RNA (mRNA) molecule is first produced from the gene via a process...
Computational methods and tools to analyze ribosome profiling data.
Somewhere in a jumble of protein building blocks may lie the key to unlocking the next generation of therapeutics to improve human health.
While it might not feel like it, the cells in our body are under constant stress. Cellular exposure to stress such as UV radiation contributes to DNA lesions that the cell responds to by initiating DNA repair pathways. If these lesions are not dealt with, mutations...
MiRNAs area class of noncoding RNA important for gene expression regulation in many plants, animals and viruses.