Surgical injury induces a system stress response which is associated with an over-activation of the innate immune response and a subsequent immunosuppression in the early post-operative period.
Anisotropic Scaffold for the Regeneration of Osteochondral Defects
A methacrylated hyaluronic acid scaffold with oriented pores perpendicular to the axial direction by an unidirectional freeze-drying method is reported.
Injectable hydrogels for precise chemotherapy
Recently, Dr. Wu and Dr. Loh have designed a biocompatible and injectable hydrogel based on thermogelling copolymer.
Nanogels for photothermal and photodynamic therapy
Marcelo Calderón and co-workers report on the design of a responsive nanogel system for a combined photothermal and photodynamic therapy of cancer. Based on a radical precipitation method, the near infrared absorbing cyanine green dye IR806 was conjugated to the macro crosslinker polyglycerol and polymerized into a thermoresponsive polyether based nanogel network.
Long-term subconjunctival delivery of brimonidine tartrate for glaucoma treatment
A long-term glaucoma treatment using drug-loaded double-polymer core-shell microspheres embedded in a porous removable carrier.
Polyphosphoesters: new trends in synthesis and drug delivery
Polyphosphoesters, with their unique features and diverse functionalities, hold tremendous potential to advance drugs carriers. Advanced synthetic tools to synthesize them efficiently and functionalization methodologies are discussed
Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Cancer Therapy
At Soochow University they have successfully prepared ultrasmall anionic-deficient WO3-x nanotheranostic probes
A new near-infrared responsive drug carrier for imaging-guided chemotherapy
A promising multifunctional nanocarrier for opto-acoustic imaging-guided chemotherapy or phtotothermal therapy is presented.
Protein cages for drug delivery
Researchers linked a polymeric transfection reagent into a hollow protein nanocage for drug delivery.
Combination of immunotherapy and nanotechnology for improved cancer treatment
Researchers have proposed a new idea to deliver anti-cancer drugs to tumor sites by combining immunotherapy and nanoparticles.