Group I intron-based trans-splicing ribozyme specifically recognizes disease-specific RNA, removes the sequence downstream of the target site, and replaces it with a 3’-exon encoding a therapeutic/reporter RNA sequence, inducing therapeutic/reporter activity selectively in the target RNA-expressing cells.
Researchers are taking advantage of 4 billion years of viral evolution to produce robust protein cages for a wide range of applications in nanotechnology.
A team of North American researchers developed an epi-SRS imaging platform for functional imaging of VSMCs in fresh coronary arteries which could support in developing new strategies for cardiovascular disease treatment.
Prof. Lei Fang reviews how co-planar conformation in π-conjugated systems can be locked by using dynamic noncovalent bonds.
The burgeoning development and sustained production of advances in the booming field of solar-to-energy conversion have inspired a Special Issue specifically dedicated to “Artificial Photosynthesis: Mimicking Nature for Renewable Energy Production” – guest editors Wee-Jun Ong, Zhiqun Lin and Kazunari Domen.
Modifications to chromatin are associated with the development of metabolic diseases, including Type 2 diabetes and obesity. There is evidence that these chromatin modifications can lead to long-term disease risk and increased disease risk for offspring.
Bioinspired, biohybrid device design and fabrication strategy for investigating the ability of therapeutics to cross the blood brain barrier.
The current special issue in Macromolecular Bioscience is published on the occasion of Professor Karel Ulbrich’s 70th birthday
This rise in the elderly population brings forward the concept of healthy aging and encourages scientists to conduct extensive research in cellular reprogramming.
![Tumor-Targeting “Polywraplex” for siRNA Delivery [Video]](https://www.advancedsciencenews.com/wp-content/uploads/2018/02/ASN_feature_adfm201703207.jpg)
Tuo Jin and colleagues from Shanghai Jiao Tong University synthesize a synthetic carrier system for small interfering RNA (siRNA) with customizable size, pH-responsive degradability, and optimized surface population of cell-targeting agent.
New theory suggests gravity is not a fundamental force
French WEST reactor breaks record in nuclear fusion
Quantum entanglement visualized for the first time ever
Higgs boson may be driving the Universe’s expansion
An anti-inflammatory peptide may hold the key to low-back pain relief
Could a nuclear explosion set Earth’s atmosphere on fire?
“Cosmic vine” discovered by the James Webb Space Telescope
Black hole images deliver a deathblow to alternative theory of gravity
The Road to Better Presentation of Data: The Do’s and Don’ts
The dramatic story behind general relativity’s Nobel Prize snub