This special issue in Macromolecular Bioscience, guest-edited by Dr. Tomáš Etrych, was initiated on the occasion of Professor Karel Ulbrich’s 70th birthday. For this birthday celebration issue, we are really happy to have assembled 12 papers written by Prof. Ulbrich’s colleagues and friends who were all influenced by his life-long scientific efforts. The contributions in this issue cover a broad range of topics related mostly to the fields of nanomedicine and controlled drug delivery.
Don’t miss out on your free access to the articles of this special issue througout 2018
Jindřich Kopeček presents drug-free macromolecular therapeutics, inducing apoptosis via calcium influx and a mitochondrial signaling pathway
Kazunori Kataoka’s contribution deals with an siRNA delivery system with responsivity toward elevated concentrations of intracellular ATP
Michal Pechar reports on anti-leukemia targeted polymer conjugates with non-covalent conjugation of the targeting protein via a coil-coiled motif
David Oupický presents novel polymer systems efficient as anti-miRNA delivery vectors with improved endosomal escape and anti-migratory activity in cancer cells
Wim Hennink and Twan Lammers describe the behavior of PEGylated polymeric nanogels
Leonard Seymour explores solid tumor immunotherapy with oncolytic viruses.
Tomáš Etrych and Petr Chytil review the recent development of pH-sensitive polymer conjugates based on hydrophilic polymers
Ernst Wagner presents EGFR-targeted and PEG-shielded pDNA lipopolyplexes
Hamid Ghandehari’s work concerns thermoresponsive recombinant silk-elastin like nanogels
Maria Jesus Vicent introduces pH-responsive polyacetal–protein conjugates suitable for polymer masked–unmasked protein therapy
Karsten Mäder contributes a study on the intended and unintended targeting of polymeric nanocarriers
Arto Urtti describes novel hyaluronic acid graft copolymers as potential drug delivery vehicles.
Together with all of the authors that have contributed to this issue, the Macromolecular Journals Team would like to express warm congratulations to Prof. Ulbrich on his 70th birthday, wishing him happiness, health and continuing success.