Recent findings on the roles and identity of the bone marrow microenvironment and how these niches might be targeted in the case of diseases are discussed.
Results for "DNA"
“Golden Age” of Molecular Microbiology: Understanding Freshwater Microbial Communities
In the “golden age” of molecular microbiology, modern molecular tools enable researchers to understand freshwater microbial communities in unprecedented detail by identifying and enumerating them, as well as determining their activity in the environment.
Engage and Move Forwards: Eukaryotic CMG Helicase Leads the Way at Replication Forks
In their review in BioEssays, Huilin Li and Michael O’Donnell discuss recent findings about the structure and function of the eukaryotic CMG helicase.
Therapeutic Applications of Group I Intron-Based Trans-Splicing Ribozymes
Group I intron-based trans-splicing ribozyme specifically recognizes disease-specific RNA, removes the sequence downstream of the target site, and replaces it with a 3’-exon encoding a therapeutic/reporter RNA sequence, inducing therapeutic/reporter activity selectively in the target RNA-expressing cells.
Public Engagement with Climate Change Imagery in a Changing Digital Landscape
There are several striking and problematic features of typical climate imagery from the perspective of engaging with wider audiences. Most notably, there is an absence of human stories – those that show ordinary and relatable humans engaging with the issue of climate change.
Synthetic Cells Gain the Upper Hand Against Cancer
Synthetic cells that function as autonomous systems for producing an anti-cancer protein inside the body are developed.
Gene Changes: Chromatin Modifications in Metabolic Disease
Modifications to chromatin are associated with the development of metabolic diseases, including Type 2 diabetes and obesity. There is evidence that these chromatin modifications can lead to long-term disease risk and increased disease risk for offspring.
Macromolecular Bioscience: Happy Birthday Karel!
The current special issue in Macromolecular Bioscience is published on the occasion of Professor Karel Ulbrich’s 70th birthday
Horizontal Transfer of Transposable Elements
In their review in BioEssays, Jean Peccoud and colleagues discuss the challenges and prospects of analyzing horizontal transfer of transposable elements on a large scale.
Cold-Inducible RNA Binding Protein in Cancer and Inflammation
Cold-inducible RNA binding protein (CIRP) in human cancers is reviewed, where it has been implicated in tumor suppression and promotion.
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