Recent advances in aptamer-mediated siRNA delivery systems for RNAi therapy ranging from anticancer therapy to antiviral therapy.
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The award-winning Wiley Interdisciplinary Reviews series combines some of the most powerful features of encyclopedic reference works and review journals in an innovative online format.
What Can Stable Isotopes of Water Tell Us About Snow Hydrology?
Insights into how melting snow is partitioned within the water cycle.
Data Assimilation in the Geosciences
The theoretical background to confront head-on the problem of data assimilation together with several examples of practical applications is provided.
Computational Methods for Analyzing and Modeling Genome Structure and Organization
Recent advances in chromosome conformation capture technologies have led to the discovery of previously unappreciated structural features of chromatin.
Assessing the Ability for Cities to Contribute to the Global Response to Climate Change
Exploration of three exciting lines of inquiry – organized around the concepts of experimentation, horizontal coordination, and vertical integration – signalling the need for greater attention to the politics and power relations that are shaping the global urban response.
Dead Sea Areas: Call for Better Management
The role of subsurface legacy sources that have lead to dead, zero-oxygen zones in the sea is assessed.
Understanding Weather and Climate of the past 300 years from Ships’ Logbooks
Ships’ logbooks dating back to the seventeenth century have helped scientists to capture different features of climate during the last centuries previously unknown.
How do People Adapt to Environmental Shocks and Stresses?
How do most people adapt to floods? What do most people do to cope with heatwaves? Which strategies to adapt to any environmental shock or stress are most common and which most rare?
Technoeconomic Assessment of Hydrothermal Liquefaction Oil from Lignin
Lignin is a by-product of the Kraft pulping process and is typically burned for energy within the pulp and paper mill plant. Due to energy efficiency measures in Kraft pulp mills, its availability has recently greatly increased. This surplus lignin provides a readily available feedstock for conversion into a phenolic-rich bio-oil via hydrothermal liquefaction (HTL).
Control of Protein Synthesis During the Integrated Stress Response
The integrated stress response (ISR) is a highly-conserved pathway used by cells to respond to diverse cellular stresses.