Researchers linked a polymeric transfection reagent into a hollow protein nanocage for drug delivery.
Results for "cancer"
Lighting up enzymatic drug release by FRET
A new generation of enzyme-responsive HPMA copolymer-drug conjugates employing a enzyme-sensitive oligopeptide linker was developed. Fluorescence resonance energy transfer (FRET) was applied to investigate the enzyme-responsive performance in both cells and animals.
Watching apoptosis in 3D
A promising approach for watching cell signaling processes in their physiological context.
Carbon-dot nanosystem for photodynamic therapy
A carbon-dot nanosystem is developed for photodynamic therapy, which releases a photosensitizer bioprecursor in cancer cells upon irradiation.
Ratiometric imaging of intact and disrupted nanocarriers
Researchers from Canada have used structure-dependent dual-wavelength emission to distinguish between intact and disrupted nanocarriers with ratiometric imaging.
Albumin–Polymer Conjugates for Drug Delivery
In their review, Jiang and Stenzel discuss the various creative approaches in which albumin can be combined with polymers for application in drug delivery.
Nanoparticles for deep-tissue photothermal therapy
Ultrasmall NdVO4 nanoparticles are presented as a promising agent for deep-tissue photothermal therapy.
Influencing the antimalarial activity of polymer-based nanomimics
A nanomimics concept based on block copolymer vesicles is evaluated with regard to molecular factors influencing antimalarial activity.
Supramolecular Fabrication of Toxin-Inspired Structures
Researchers have devised a bottom-up approach to fabricate precisely arranged synthetic macromolecules and an enzymatically active toxin from Clostridium botulinum.
Versatile Protein Nanogels
Zhen Gu at Joint UNC/NC State Department of Biomedical Engineering gives an overview of the recent advances in protein nanogels for biomedical applications
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