Lead Optimization for Medicinal Chemists
PART I: INTRODUCTION The Drug Discovery Process Lead Optimization PART II: THE PHARMACOKINETIC PROPERTIES OF COMPOUND CLASSES Alkanes Alkenes and Alkynes Arenes Halides Azides Nitro Compounds Azo Compounds Triazenes Nitrates and Nitrites N-Nitroso Compounds N-Oxides Alcohols Phenols Ethers Epoxides Peroxides Thiols Thioethers Sulfoxides Sulfones Aliphatic Amines Quaternary Ammonium Salts Amidines Guanidines, Acylguanidines, and Biguanides […]