Lead Optimization for Medicinal Chemists

by | Apr 20, 2012

  PART I: INTRODUCTION The Drug Discovery Process Lead Optimization PART II: THE PHARMACOKINETIC PROPERTIES OF COMPOUND CLASSES Alkanes Alkenes and Alkynes Arenes Halides Azides Nitro Compounds Azo Compounds Triazenes Nitrates and Nitrites N-Nitroso Compounds N-Oxides Alcohols Phenols Ethers Epoxides Peroxides Thiols Thioethers Sulfoxides Sulfones Aliphatic Amines Quaternary Ammonium Salts Amidines Guanidines, Acylguanidines, and Biguanides […]
  PART I: INTRODUCTION

The Drug Discovery Process
Lead Optimization

PART II: THE PHARMACOKINETIC PROPERTIES OF COMPOUND CLASSES

Alkanes
Alkenes and Alkynes
Arenes
Halides
Azides
Nitro Compounds
Azo Compounds
Triazenes
Nitrates and Nitrites
N-Nitroso Compounds
N-Oxides
Alcohols
Phenols
Ethers
Epoxides
Peroxides
Thiols
Thioethers
Sulfoxides
Sulfones
Aliphatic Amines
Quaternary Ammonium Salts
Amidines
Guanidines, Acylguanidines, and Biguanides
Anilines
Hydrazines, Acylhydrazines, and Hydrazones
Aldehydes
Ketones
Carboxylic Acids
Carboxylic Esters
Amides
Lactams and Imides
Nitriles
Carbonates
Carbamates
Ureas
Thiocarbonyl Compounds
Sulfonic Acids
Sulfonic Esters
Sulfates and Sulfamic Acids
Phosphonic Acids
Phosphoric Acid Derivatives
N-(Aminoalkyl)benzamides, -benzoates, and Related Compounds
Arylalkylamines
Phenethylamines (2-phenylethylamines)
Aminoalkylindoles and Indole Alkaloids
Pehenothiazines
Dibenzazepines and Related Tricyclic Compounds
3-Aryloxy-2-Hydroxypropylamines (ß-Adrenergic Antagonists; ‘Beta Blockers’)
Opiates
N-(Carboxyalkyl)-alpha-Amino Acid Amides (Prils)
Anilides and Amindes of Glycine
Peptides, Peptidomimetics, and Related Oligoamides
Oligoarylamines, -amides, -carbamates, and -ureas
Imidazoles
Triazoles
Pyridines, Pyrimidines, and Related Compounds
Quinolines
Nucleoside Analogs
Dihydropyridines
Arenesulfonamides
[XVI, 606 Pages, Hardcover]

Read More…

Related posts:

New Book Series “Nanotechnology Innovation and Applications”

New Book Series “Nanotechnology Innovation and Applications”

New book series “Nanotechnology Innovation and Applications” – out now! The book series “Nanotechnology Innovation and Applications” was initiated and overseen by Prof. Dr. Dr. h.c. Marcel Van de Voorde who has more than 40 years’ experience in European research...

Nanotechnology for the Energy Challenge, 2nd Edition

The 2nd edition of Nanotechnology for the Energy Challenge is now available to purchase. This exceptional monograph provides an overview of the subject, and presents the current state of the art with regard to different aspects of sustainable production, efficient...

Lampenfieber vor Präsentationen ?

Die neue Auflage von „Professionell Präsentieren in den in den Natur- und Ingenieurwissenschaften“ vermittelt die Vortragstechniken und Soft Skills, die speziell in den Naturwissenschaften eine Rolle spielen.

Aphorismen und Zitate über Natur und Wissenschaft

Inspirierend, witzig und zum Nachdenken anregend beschreibt Hans-Jürgen Quadbeck-Seeger nichts weniger als das Leben in all seinen (naturwissenschaftlichen) Facetten - mit Aphorismen, die oft "die Weisheit eines ganzen Buches in einem einzigen Satz" zusammenfassen...