A research team combats antibiotic-resistant superbugs by administering antibiotics together with metformin.
Therapeutics
A new deep-learning architecture for drug discovery
Convolutional neural networks provide stronger predictive performances for pharmacological assays compared to traditional machine learning models.
Tracking and analysis of SARS-CoV-2 spike protein mutations
Understanding changes to the spike protein’s structure is critical to the development of an effective vaccine.
Screw cancer: Microneedle sticks it to cancer tissue
Scientists are finding safer ways to keep drug-loaded microrobots attached to cancer tissue.
Predicting the behavior of macromolecules
Researchers at Houston Methodist Research Institute discuss how quantitative, non-invasive imaging can aid in developing novel tools for diagnosis and therapy.
Does the dusk of “old-school antibiotics” mean the dawn of antimicrobial nanomaterials?
Antibiotic-resistant bacteria are becoming a major global threat. Novel antibacterial nanomaterials offer a solution.
Killing cancer with iron
Researchers at the University of Munich have demonstrated a conceptually novel nanocarrier strategy in which the nanoparticles are both the cargo and the carrier.
Recruiting AI in the battle against SARS-CoV-2 and future pandemics
A new AI system can identify optimal combinations of drugs and dosages in a matter of days to help halt viral pandemics before they reach global scales.
Study finds remdesivir effective against a key enzyme of coronavirus that causes COVID-19
Remdesivir, an anti-viral agent known to be effective against MERS, is already in human trials as researchers search for a treatment for COVID-19.
A new, inhaled siRNA therapeutic option for asthma
A nanocarrier that can deliver siRNA into the lungs is investigated for the treatment of severe asthma and other lung diseases.
Conserved elements in viral genomes may provide targets for broad-spectrum drugs
RNA elements that are found in the genomes of numerous representatives within the same virus family provide new opportunities to expand the repertoire of targets for the development of antiviral therapy.
Targeting the untargetable and treating the untreatable
A blackboard of therapeutic innovation: Researchers seek to understand how antisense oligonucleotides can “erase” disorders.
Multifunctional nanomedicine: Developing smarter therapeutics
The Lahann Lab at the University of Michigan discusses how nanomedicine benefits by bridging biology, engineering, and materials.
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