Poly(2-oxazoline)s – a platform for well-defined polymer architectures and biomaterials

by | Oct 18, 2012

A special issue in Macromolecular Rapid Communications has been dedicated to poly(2-oxazoline)s & related pseudo-polypeptides - a growing field of research.

The class of poly(2-oxazoline)s (POx) was first reported in the literature in 1966. Research in this area has been re-stimulated by the introduction of microwave reactors which helped to overcome the problem of long polymerization times.

Recently POx and related pseudo-polypeptides have been investigated for their great potential in biomedical and life science applications. They are quite readily available, their chemical structures and physical properties can be precisely controlled and adjusted, and they have excellent biocompatibility. One of the current limiting factors is the lack of regulatory approval by the Food and Drug Administration (FDA). Nevertheless, research in this area is rapidly expanding, both synthetically and with regard to applications.

Two of the leading figures in the field of POx, Helmut Schlaad (Max Planck Institute of Colloids and Interfaces, Potsdam, Germany) and Richard Hoogenboom (Ghent University, Belgium) have now guest-edited a special issue to further stimulate research in this exciting area.

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