One-shot radical polymerization for hydrogels

by | Jun 12, 2020

Synthesis of multi-purpose double network hydrogels via one-shot radical polymerization.

 Image credit: Jong Marshes on Unsplash

Due to functionality which includes water absorption and retention, permeability, and biocompatibility, hydrogels are used for a wide variety of key applications. The utilization of hydrogels ranges from self-healing materials to biomedical applications, such as contact lenses and tissue engineering, to superabsorbent materials and far beyond.

Double network hydrogels incorporate high swelling and mechanical properties. Preparation of previously reported double network hydrogels has generally been performed by a two-step polymerization, whilst few studies have explored a simple one-shot polymerization method for the fabrication of gels having a structure in which both networks are connected by chemical crosslinking.

In a recently published article in Polymer International, Akikazu Matsumoto and co-workers have described the efficient synthesis of DN hydrogels, examining several one-shot polymerization systems consisting of two kinds of monomers and two kinds of crosslinkers with different reactivity.

The novel materials were synthesized by a one-shot radical polymerization of an ionic monomer for the first network and a non-ionic monomer for the second network. Even though the monomers were added simultaneously, the polymerization of the second monomer was delayed. This “one-shot, two-step” polymerization has the unique advantage that the synthetic processes, including the order of the polymerization of two kinds of monomers, are tuneable.

Looking forward, the authors note that “further investigation of the combination and the control of the reactivity of the used monomers will be required in order to fabricate the true DN gels with higher strength and toughness” by this polymerization process.

Reference: Dohi, S., Suzuki, Y. and Matsumoto, A. ‘One‐shot radical polymerization of vinyl monomers with different reactivity accompanying spontaneous delay of polymerization for the synthesis of double network hydrogels.’ Polymer International. (2020). DOI: 10.1002/pi.6048