M. Mehdizadeh and J. Yang present a review of the development of tissue adhesives and sealants which, over the past couple of decades, have revolutionized bleeding control and wound healing. The structure, composition, functioning mechanisms, and performance of clinically used hemostatic agents, tissue adhesives, and sealants are considered.
Reported applications and limitations of each adhesive system are looked at from a clinical standpoint. Furthermore, the latest advances in the development of new tissue adhesives as well as emerging applications in regenerative medicine are also discussed.
